Is Endoscopy Painful? What It Feels Like

Is endoscopy painful? Most patients feel little to no pain thanks to sedation. Learn what the procedure actually feels like before , during and after.

ENDOSCOPY

Dr Qi Rui

12/20/20255 min read

This is one of the most common questions patients ask before scheduling an endoscopy. The idea of a flexible tube going down the throat sounds uncomfortable at best and painful at worst. It's a reasonable concern. But the reality is far less dramatic than most people imagine.

The short answer? Most patients feel little to no pain during endoscopy. The procedure is performed under sedation , which means patients are in a relaxed , drowsy state throughout. Many don't remember the examination at all. Those who do recall bits and pieces typically describe pressure or mild discomfort rather than actual pain.

That said , the experience varies. Sedation levels differ. Individual pain thresholds differ. The type of endoscopy matters too. Understanding what endoscopy involves helps set realistic expectations about sensations before , during and after the procedure.

What Happens During the Procedure

Before discussing pain specifically , it helps to understand what's actually happening. During a standard upper GI endoscopy , the physician passes a thin flexible scope through the mouth , down the throat , into the stomach and through to the duodenum. The scope is about the width of a finger. It contains a camera , light source and channels for instruments.

The endoscopy procedure typically takes 10 to 30 minutes. Patients lie on their left side. A mouth guard protects the teeth. The scope passes through while patients continue breathing normally since it doesn't block the airway.

Now here's the key part. Almost all endoscopies are performed with sedation. This changes everything about the experience.

The Role of Sedation

Sedation is what separates a potentially uncomfortable procedure from one that most patients barely remember. The American Society for Gastrointestinal Endoscopy notes that the vast majority of endoscopic procedures use some form of sedation to ensure patient comfort.

Most facilities use moderate sedation , sometimes called conscious sedation or twilight sedation. Patients receive medication through an IV that induces a relaxed , drowsy state. They're not fully unconscious like with general anesthesia , but they're not fully aware either. It's somewhere in between.

The medications work quickly. Within minutes , patients feel calm and sleepy. Many drift off entirely. Others remain in a dream-like state where they're technically awake but deeply relaxed and unlikely to form memories of what's happening.

Common sedation medications include midazolam (a benzodiazepine that reduces anxiety and creates amnesia) and fentanyl (an opioid that provides pain relief). Many facilities now use propofol , which works faster and wears off more quickly. The specific combination depends on the facility , the physician's preference and the patient's medical history.

Here's what patients typically report after waking up: they remember being in the procedure room , then suddenly they're in recovery being offered juice and crackers. The examination itself? A blank. This amnesia effect is intentional and is one reason why endoscopy is far less distressing than it might sound on paper.

What Patients Actually Feel

Even with sedation , some patients retain partial awareness or vague impressions of the procedure. What do they describe?

Pressure rather than pain. The most common sensation is pressure in the throat or chest as the scope passes through. This isn't sharp or stabbing. It's more like the feeling of swallowing something slightly too large. Uncomfortable perhaps , but not painful.

Gagging reflex. Some patients experience brief gagging when the scope first enters the throat. This is a natural reflex. The sedation typically suppresses it significantly , but it may not eliminate it entirely. Physicians expect this and work quickly through the initial insertion.

Bloating. Air is pumped into the stomach during the procedure to expand it for better visualization. This can cause a sensation of fullness or bloating. Some patients feel the urge to burp. Again , this is pressure rather than pain.

Nothing at all. Many patients genuinely feel and remember nothing. They close their eyes in the procedure room and open them in recovery. For these patients , the question of whether endoscopy is painful becomes irrelevant. They simply weren't aware enough to perceive any sensations.

According to Mayo Clinic , most patients tolerate endoscopy very well , and serious discomfort during the procedure is uncommon when appropriate sedation is used.

Factors That Affect Comfort

Not everyone has the same experience. Several factors influence how comfortable or uncomfortable an endoscopy feels.

Sedation depth. Deeper sedation generally means less awareness and less discomfort. Patients who metabolize medications quickly or who have high tolerance may remain more aware than others. Physicians can adjust dosing , but individual responses vary.

Anxiety levels. Patients who are extremely anxious beforehand may have more difficulty relaxing even with sedation. Pre-procedure anxiety can heighten perception of discomfort. Some facilities offer anti-anxiety medication before the sedation to help patients start from a calmer baseline.

Anatomy. Some patients have anatomical variations that make scope passage slightly more challenging. A narrow esophagus , large hiatal hernia or other structural factors can affect the procedure. Experienced endoscopists navigate these variations routinely , but they may contribute to slightly more sensation.

Gag reflex sensitivity. People with highly sensitive gag reflexes may experience more gagging despite sedation. Throat spray with local anesthetic can help numb this reflex. Letting the medical team know about gag reflex concerns beforehand allows them to take extra measures.

Procedure complexity. A straightforward diagnostic endoscopy typically causes less discomfort than one involving therapeutic intervention. If the physician needs to dilate a stricture , remove large polyps or perform other treatments , the procedure takes longer and may involve more manipulation.

Unsedated Endoscopy: A Different Experience

While uncommon in many countries , some patients do undergo endoscopy without sedation. This might happen by patient choice , due to medical contraindications to sedation or because of facility practices in certain regions.

Unsedated endoscopy is more uncomfortable. Patients remain fully aware throughout. They feel the scope passing through the throat and may gag more significantly. However , even without sedation , the procedure isn't typically described as severely painful. Uncomfortable and unpleasant , certainly. But the scope doesn't cause tissue damage during normal passage , so there's no sharp pain.

Patients who choose unsedated endoscopy often do so to avoid sedation side effects , to drive themselves home afterward or because they've had the procedure before and know they tolerate it well. It's not the right choice for everyone , but it demonstrates that even at maximum awareness , endoscopy remains tolerable for many people.

After the Procedure: What to Expect

Post-procedure sensations matter too. What does recovery feel like?

Sore throat. This is the most common complaint after endoscopy. The throat may feel scratchy , raw or mildly sore for 1 to 2 days. This results from the scope passing through and is temporary. Warm liquids , throat lozenges and soft foods help ease the discomfort.

Bloating. Residual air in the stomach can cause bloating and the urge to burp for several hours. Walking around helps move the air through. This resolves on its own.

Grogginess. Sedation effects linger for several hours. Patients may feel drowsy , slightly confused or unsteady. This isn't painful but can be disorienting. It's why driving and important decisions are off-limits for the rest of the day.

Mild cramping. Some patients experience mild abdominal cramping , especially if biopsies were taken. This typically resolves within a day.

Severe pain after endoscopy is not normal and should prompt a call to the physician. It could indicate a rare complication like perforation. But for the vast majority of patients , post-procedure discomfort is mild and short-lived.

Putting Fear in Perspective

Fear of pain keeps some people from getting endoscopies they need. This is unfortunate because the anticipated discomfort almost always exceeds the actual experience. Most patients leaving the recovery room say some version of "that was easier than I expected."

The combination of effective sedation , experienced physicians and modern equipment makes endoscopy one of the more tolerable invasive procedures in medicine. It's not something anyone looks forward to , but it's also not something to dread.

For patients with significant anxiety , talking to the medical team beforehand helps. They can explain exactly what to expect , discuss sedation options and address specific concerns. Knowing what's coming reduces fear. And less fear often means a smoother experience overall.

The bottom line? Endoscopy isn't painful for most patients. It's a brief procedure performed under sedation that provides valuable diagnostic information. The temporary mild discomfort is a small price for the answers it delivers.